Endocrine Abstracts

Introduction: Cortisol level measurement is required in the diagnosis and management of adrenal, pituitary and hypothalamic pathologies.Aim: The aim of this study was to evaluate clinician’s practice in ordering cortisol test.Methods: A retrospective study concerning 63 cortisol requests data collected by the laboratory computer system (Health Lab) between January 2024 and February 2024. Only requests of 0800 hours plasma cort...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrinopathy caused by inappropriate PTH secretion by the parathyroid glands, which leads to alterations in phosphocalcic metabolism. The aim of our study is to determine the prevalence of complications of PHPT.Materials and Methods: Retrospective descriptive study of 83 patients with primary hyperparathyroidism collected over a period of 07 years (between 2015 and 2022) in the endocrinology ...

Introduction: Inappropriate laboratory test utilization can result in unnecessary patient testing and increased healthcare costs. Thyroid-stimulating hormone (TSH) is recommended as the first-line test for investigating and monitoring thyroid dysfunction. We evaluate Thyroid function tests (TFTs) ordering in our hospital practice.Methods: A retrospective descriptive study included 400 TFTs requests. TFTs of interest were: TSH and FT4. These tests request...

Introduction: DiGeorge syndrome is a genetic abnormality caused by a microdeletion of chromosome 22. Chromosome 22q1 1.2 microdeletion was first identified in 1992 as the common genetic anomaly associated with a range of conditions previously known as DiGeorge or velocardiofacial syndrome.Case report: A 17-year-old Moroccan male was mildly mentally challenged and had seizures from the age of 9 years. He had dysmorphic facial features, and mild tortuosity...

Introduction: Mitochondrial diabetes (DM) is a monogenic form of maternal transmission diabetes that is caused by mutations in the mitochondrial genome. These mutations affecting mitochondrial function may be the cause of initiation of the phenomenon of apoptosis itself having an aggravating role of the phenotype in patients with mitochondrial diabetes.Materials and Methods: This study involved 43 patients with mitochondrial diabetes (20 non-syndromic an...

Introduction: Sexual disorders 46 XY DSD are responsible for a range of phenotypic disorders, ranging from an ambiguous phenotype to a complete female phenotype. In this context, we report a cohort of 22 46 XY patients with a female phenotype in order to establish a phenotype-genotype correlation.Results: The average age at diagnosis was 15.5 years (E: 7 days-33 years). The reason for consultation was primary amenorrhea in 16 cases (72.7%), sexual ambigu...

Background and Aims: Several studies have pointed a significant relationship between diabetic complications, glycemic imbalance, and the onset of lower urinary tract dysfunction (LUTD) in this population. The current survey aims to assess the clinical and biochemical characteristics related to glycemic control in patients with type 2 diabetes presenting with symptoms of LUTD.Patients and Method: We conducted a comparative cross-sectional study that inclu...

Introduction: Diabetes, like any chronic disease, generates in addition to the somatic consequences, serious psychological repercussions, depression and diabetes emerging respectively in the 4th and 9th rank of the most important causes of disturbances in number of years of life corrected for the disability factor. (DALYS).Patients and methods: Descriptive retrospective study of 38 post-Covid diabetics collected from the endocrinology – diabetology ...

Introduction: Metabolic syndrome (MS) is responsible for the increased cardiovascular risk in type 2 diabetics, but few studies have looked at the metabolic syndrome in type 1 diabetics. The aim of This study is to evaluate the prevalence of microvascular and macrovascular complications and evaluate the cardiovascular risk among patients with T1DM associated with metabolic syndrome.Materials and Methods: Retrospective study which included 36 type 1 diabe...

Introduction: Mixed connective tissue disease (MCTD), also known as Sharp´s syndrome is a rare autoimmune disease (AD), characterized by the presence of high titers of a distinctive autoantibody: ribonucleoprotein auto-antibody (anti-RNP). It presents with varied overlapping symptoms of different connective tissue disorders which may appear sequentially over time. As other AD, MCTD may be associated with one or more AD, such as autoimmune thyroid disorders (AITD).<p c...